Episode 139: Lassa virus genomics
📅19 June 2025
⏱️00:15:29
🎙️Microbial Bioinformatics
👥Guest
Sara Zufan
ORISE Postdoctoral Fellow, USDA/NIH
On this episode we are joined by Sara Zufan to discuss her PhD journey and recent projects. The episode covers various research experiences and challenges in the field, including the rapid detection of AMR using nanopore sequencing, COVID-19 projects, hepatitis A outbreak investigations, and Lassa virus surveillance in Liberia.
The guests share insights into their professional journeys, their experiences working across different continents, and the future of microbial bioinformatics research.
Key Points
1. Research Trajectory
- Completed PhD exploring intersection of public health and genomics
- Worked on rapid AMR detection using nanopore sequencing
- Conducted COVID-19 and hepatitis A research projects
2. Lassa Virus Research
- Currently developing wastewater surveillance for Lassa virus in Liberia
- Working on understanding viral genetic diversity and genomic detection methods
- Collaborating with NIH and USDA on one-health approach to pathogen monitoring
3. Interdisciplinary Approach
- Combines wet lab and computational techniques
- Experienced in international research environments (Australia, USA, Liberia)
- Skilled in genomic sequencing and bioinformatics analysis
Take-Home Messages
- Interdisciplinary skills are crucial in modern microbial research
- Emerging pathogens require innovative genomic surveillance strategies
- International collaboration is key to understanding complex biological systems