Episode 144: Micro binfie Pathoplexus part 1
📅11 September 2025
⏱️00:22:47
🎙️Microbial Bioinformatics
👥Guests
Molecular Epidemiologist, Swiss Tropical and Public Health Institute
Assistant Professor, London School of Hygiene and Tropical Medicine
Independent Bioinformatics Consultant
The microbinfie podcast explores Pathoplexus, an innovative platform designed to facilitate viral genome data sharing while addressing researchers' concerns about publication credit and data accessibility.
Nabil and Lee bring a guest host Clint to talk with some of the people behind Pathoplexus http://pathoplexus.org/
Key Points
1. Pathoplexus Platform
- Virus genome database allowing researchers to share sequences
- Supports both open and restricted-use data sharing models
- Provides immediate pre-processing of uploaded sequences using tools like Nextclade
2. Data Sharing Innovation
- Addresses researchers' fear of being "scooped" through restricted-use option
- Allows public health use of sequences before publication
- Supports aggregate analysis while protecting individual researchers' interests
3. Community-Driven Development
- Currently hosts genomic data for viruses like Ebola, West Nile, mPox, RSV
- Selects new pathogens based on community input and public health needs
- Implements innovative citation tracking through sequence set DOIs
Take-Home Messages
- Pathoplexus revolutionizes viral genomic data sharing
- Balances open science with researchers' publication concerns
- Provides flexible, community-responsive platform for pathogen genomics