Episode 145: Micro binfie Pathoplexus part 2
📅25 September 2025
⏱️00:20:52
🎙️Microbial Bioinformatics
👥Guests
Molecular Epidemiologist, Swiss Tropical and Public Health Institute
Assistant Professor, London School of Hygiene and Tropical Medicine
Independent Bioinformatics Consultant
In this episode of the microbinfie podcast, the hosts discuss Pathoplexus, an innovative pathogen genomics database with a unique community-driven governance model and open-source approach.
Nabil and Lee bring a guest host Clint to talk with some of the people behind Pathoplexus http://pathoplexus.org/
Key Points
1. Database Governance
- Established as a Swiss 'Verein' (association) with community accountability
- Members can vote out executive board if unsatisfied with direction
- Designed to serve the pathogen genomics and public health community
2. Open-Source and Transparency
- Everything is open-source and hosted on GitHub
- Users can raise issues, request features, and report sequence errors
- Encourages community participation and continuous improvement
3. Data Sharing and Commercial Use
- Allows sequence uploads with flexible usage terms
- Acknowledges challenges of pathogen access and benefit sharing
- Aims to remain adaptable to future global solutions
Take-Home Messages
- Community-driven databases can revolutionize scientific data sharing
- Transparent governance is crucial for scientific infrastructure
- Open-source platforms enable rapid iteration and community engagement